Unveiling the power of tinted sunscreens in reducing melasma hyperpigmentation: A systematic review

Summary: Abstract Body: This study investigates the efficacy of tinted versus non-tinted sunscreens in mitigating hyperpigmentation in patients with melasma, focusing on clinical outcomes and patient satisfaction. A systematic review of peer-reviewed studies published from 2010 to 2025 was conducted, including trials evaluating tinted and non-tinted sunscreens in melasma management. Key metrics analyzed included reductions in the Melasma Area and Severity Index (MASI), changes in skin reflectance (ΔL*), and patient-reported outcomes.The results indicate that tinted sunscreens demonstrated significantly greater reductions in MASI scores (30-40%) compared to non-tinted sunscreens (15-25%) over similar treatment durations (p = 0.027). Patients using tinted sunscreens also reported higher adherence and satisfaction, attributed to enhanced visible light protection provided by iron and titanium oxides.These findings underscore the superior efficacy of tinted sunscreens in managing melasma, highlighting their potential as a critical component of treatment strategies. This study emphasizes the need for future clinical trials to evaluate long-term outcomes and solidify tinted sunscreens’ role in hyperpigmentation therapy. Arielle M. Radparvar¹, Attiya Haroon² 1. California Health Sciences University College of Osteopathic Medicine, Clovis, CA, United States. 2. Rao Dermatology, Fresno, CA, United States. Pigmentation, Melanoma, and Melanoma Immune Surveillance