Utilizing the VISIA camera for analyzing 5-Fluorouracil treatment efficacy for actinic keratoses

Summary: Abstract Body: The VISIA camera is a novel device that captures images of the skin using a rotating camera with both UV and polarized light, assessing the condition of both surface and subsurface skin . It provides patients with an easy-to-understand analysis regarding their skin’s problem areas allowing for targeted treatment options. Actinic Keratoses (AKs) are precancerous lesions that are diagnosed through clinical examination and dermoscopy. Incorporating VISIA imaging for AK patients may offer a deeper understanding of sun damage and serve as a tool to encourage adherence to field treatment, such as 5-Fluorouracil (5-FU). In this observational study, we evaluated a male patient diagnosed with diffuse AKs who was prescribed and had consented to go through 5-FU treatment on the scalp. Baseline VISIA photos were taken prior to treatment, and 5-FU was applied twice daily to the scalp for four weeks. Follow-up imaging was obtained one week and three months post-treatment. Analysis using the UV spot filter revealed a reduction in feature count from 706 to 631 and an improvement in the percentile which reduced from 83% to 39%. Spot filter produced the same percentile of 9% for all photos affirming the VISIA’s efficacy in detecting UV damage-related areas. These findings demonstrate the VISIA camera’s utility for documenting treatment progress while enhancing patient education and motivation for treatment adherence. By illustrating the effectiveness of 5-FU in treating AK’s, VISIA serves as a compelling tool for promoting patient understanding and encouraging adherence to future treatment plans. Emily G. Woolhiser¹, Colin Burnette², Jake Nusynowitz³, Bertha Baum⁴, Robert Dellavalle⁵ 1. Kansas City University College of Osteopathic Medicine, Kansas City, MO, United States. 2. Nova Southeastern University, Fort Lauderdale, FL, United States. 3. Florida International University, Miami, FL, United States. 4. Larkin Community Hospital Graduate Medical Education, South Miami, FL, United States. 5. University of Minnesota Twin Cities, Minneapolis, MN, United States. Clinical Research: Epidemiology and Observational Research