UTILITY OF WORST PATTERN OF INVASION IN GUIDING ADJUVANT TREATMENT IN EARLY STAGE ORAL CAVITY CANCER

Summary: There are several pathologic risk factors that influence post- operative management of early-stage oral cavity squamous carcinoma (OSCC). The worst pattern of invasion (WPOI), ranging from I-V, is a known prognosticator for OSCC, specifically WPOI-5. Because it remains optional in pathology reporting, it is not widely utilized to guide adjuvant therapy of early stage OSCC. Our study aims to analyze clinical outcomes with early stage OSCC and WPOI-5 to determine whether WPOI-5 is an indication for adjuvant radiation therapy in this population