A rare case report of a teenage girl with pemphigus vegetans in Mongolia

Summary: Abstract Body: Pemphigus is a group of autoimmune blistering diseases of the skin and mucous membranes characterized by histologically intraepidermal blisters due to the loss of cell–cell adhesion of keratinocytes. In general, it ranges from 0.76 to 5 new cases per million per year. The mean age of onset of a disease is 50 to 60 years old. Pemphigus vulgaris is the most common type of pemphigus, presenting with mucocutaneous bullae, while pemphigus vegetans is the rarest variant, accounting for only 1-2% of cases and typically affecting middle-aged individuals. We report the first child case of the pemphigus vegetans in Mongolia. A 13-year-old girl presenting with mucous erosions, many cauliflower like plaques in the axilla, inframammary, inguinocrural, and intergluteal areas visited the National Dermatology Center of Mongolia. This girl was previously misdiagnosed and mistreated as sexually transmitted disease. We diagnosed the patient with pemphigus vegetans based on skin biopsy results, and positive Dsg1 and 3 results. Tsogzol Gungaanyam³, Khulan Ayush³, Otgonjargal Zandargombo³, Uranchimeg Tseden-Ish¹, Delgerzaya Enkhjargal² 1. Administration Department, National Dermatology Center, Ulaanbaatar, Mongolia. 2. Department of Laboratory, National Dermatology Center, Ulaanbaatar, Mongolia. 3. Outpatient Department, National Dermatology Center, Ulaanbaatar, Mongolia. Clinical Research: Epidemiology and Observational Research