The impact of socioeconomic and demographic factors in the utilization of mohs surgery for the treatment of sebaceous carcinoma

Summary: This study aims to evaluate the impact of demographic and socioeconomic factors including metropolitan/nonmetropolitan residential status on the utilization of MOHS surgery for the treatment of sebaceous carcinoma. A retrospective, population-based study was conducted using the Surveillance, Epidemiology, and End Results (SEER) Research Plus 17 Registries database. SEER was queried for all cases of sebaceous carcinoma (ICD-O-3/3 code 8410) diagnosed between 2000 and 2021 with extracted variables of interest including age at diagnosis, sex, race in terms of white versus non-white, cause of death, median household income per county, and metropolitan versus nonmetropolitan residential status. Statistical analysis included chi-square and logistic regression performed using SPSS software with significance set to p < 0.05. Chi square analysis revealed no statistically significant difference in the utilization of MOHS surgery for patients in metropolitan and nonmetropolitan counties (p=0.508). There was no statistically significant difference in deaths attributable to sebaceous carcinoma between metropolitan and nonmetropolitan counties (p=0.299). Patients that received MOHS surgery were more likely to be white (odds ratio=1.207, p=0.045), less likely to be 70 years old or older (odds ratio=0.851, p=0.024), and more likely to live in a county with a median income greater than $75,000 (odds ratio=1.218, p=0.010). Those that died from sebaceous carcinoma were less likely to be female (odds ratio=0.674, p=0.014) and more likely to be greater than or equal to 70 years old (odds ratio=1.562, p=0.005). The SEER Research Plus 17 Registries database offers the largest collection of sebaceous carcinoma cases to date. The results of this study provide insight into the impact of socioeconomic and demographic factors for the utilization of MOHS surgery for patients with sebaceous carcinoma. Joseph Cascone¹, Priya Patel¹, Julian Vallejo¹, Michael Siscos¹ 1. University of Missouri-Kansas City, Kansas City, MO, United States. Clinical Research: Epidemiology and Observational Research