P53 OVEREXPRESSION MAY REPRESENT AN EARLY MARKER OF CLINICOPATHOLOGIC PROGRESSION IN VASCULOGENIC MESENCHYMAL LESIONS OF GERM CELL TUMOR ORIGIN
Reem Youssef
Guru | Pathology
Presented at: USCAP
Date:
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Summary: P53 overexpression is associated with disease progression in a subset of VMTs and may precede the morphologic changes associated with this phenomenon. Routine evaluation of VMTs with p53 IHC seems justified, with overexpressors likely requiring an aggressive clinical approach.