A Missed Zebra: A Case Report of the Postmortem Diagnosis of Vascular Ehlers-Danlos Syndrome (vEDS)

Summary: Postmortem genetic testing confirmed a diagnosis of vascular Ehlers-Danlos syndrome (vEDS) in a young man who died from a ruptured aneurysm. Subtle clinical signs, including prominent eyes and joint dislocation, were overlooked. The genetic findings prompted screening for at-risk family members, highlighting the critical role of autopsy in identifying inherited disorders and preventing future tragedies.